Excessive Doses of Opium.

Patient-specific electronic decision support reduces prescription of excessive doses.

OBJECTIVES Prescription of excessive doses is the most common prescription error, provoking dose-dependent adverse drug reactions. Clinical decision support systems (CDSS) can prevent prescription errors especially when mainly clinically relevant warnings are issued. We have built and evaluated a CDSS providing upper dose limits personalised to individual patient characteristics thus guaranteei...

Opium

of opium. Indeed, there can be few (if any) officials in authority, either in India or China, having, or who could be reasonably expected to possess, more than a very general impression regarding the subject. Yet, in many districts in India, the use of opium is as common as in China itself. On the other hand, there are numerous medical officers, who, from personal experience and observation, of...

Effect of hypoadrenalism and excessive doses of desoxycorticosterone acetate upon response of the rat to ouabain.

The influence of alterations of adrenal function upon the responsiveness of the rat to intravenously administered ouabain was studied electrocardiographically by the string galvanometer. Conduction disturbances followed by cardiac arrest were the criteria for a definitive response. Adrenalectomized rats showed a significant increase in sensitivity to ouabain as compared with normal controls. No...

The absorption and excretion of calcium and phosphorus by rats receiving excessive doses of irradiated ergosterol.

Opium-Eating

IN the January, 1872, number of the Indian Medical Gazette is an article on "Opium," written by Dr. Moore, wherein that gentleman states that, from personal observation, he arrives at the conclusion, " that opium-eating when moderately indulged in?as it generally is?produces no decided or even appreciable ill effect." Moreover, that the use of opium, under certain circumstances, is beneficial. ...